Protein Information

General Information
MoonProt ID143
First appeared in release1.0
Name(s)citrate synthase
UniProt ID I7MG78
GO termsGO:0006099 tricarboxylic acid cycle GO:0044262 cellular carbohydrate metabolic process GO:0016740 transferase activity GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer GO:0005856 cytoskeleton
Organisms for which functions have been demonstratedTetrahymena thermophila
Sequence length474
FASTA sequence>tr|I7MG78|I7MG78_TETTS Citrate synthase OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_00318570 PE=3 SV=1 MRKQIINCKRLYHQNQYFFNPKADLKTVLREQIPIKIQGFNEMKKKYGDRVMGEITVNQALGGMRGIRALFYDQSTVDPIDGVMFRGYSIPELHELLPKLRKPSAEDFQSDQQPLPEGLFFLLLTGELPSYHQVELIRHEWDVRGKVSDELINFINRLDNKMHPMTMLSLAILYEQKTSKFAQLYNESKLNKSNYWEYTYEDSVDLIAKLPRIAATIYRKKFKDGKPIAHKDGLDWSAQLAHMMGFEGQETLNELLRAFLTIHADHEGGEVSTHASHLVGSALGDPYLCMTTAYTGLAGPLHGLANQEVLKWILNFVEVHGYDVTNRQIEDYVNTTVLSGRLVPGYGHAVLRRPDPRFLHLYDFGNKYLRDNEMIRLLHQMTDVIPRRLRTFKNISSPYPNVDCHSGALLYQLGIQEYQFYTVLFAISRSIGCLTNLVWCRAFGLPIERPESADLAYYNNLFQNKIPKQEKDDQ
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptioncitrate synthase, enzyme acetyl-CoA + oxaloacetate + H2O => citrate + CoA-SH Citric acid cycle
References for functionNumata, Osamu, et al. "Tetrahymena 14-nm filament-forming protein has citrate synthase activity." Biochemical and biophysical research communications 174.2 (1991): 1028-1034.
E.C. number2.3.3.1
Location of functional site(s)
Cellular location of function
Comments
Function 2
Function description14-nm cytoskeletal protein
References for functionNumata O. Multifunctional proteins in Tetrahymena: 14-nm filament protein/citrate synthase and translation elongation factor-1 alpha. Int Rev Cytol. 1996 0. PMID: 8575889
E.C. numberN.A
Location of functional site(s)
Cellular location of functioncytosol, cytoskeleton
Comments