Protein Information

General Information
MoonProt ID146
First appeared in release1.0
Name(s)hemagglutinin HA
UniProt IDB9VJ59 (B9VJ59_9PARA), Unreviewed
GO termsGO:0008152 metabolic process GO:0016032 viral process GO:0019058 viral life cycle GO:0019062 virion attachment to host cell GO:0046718 viral entry into host cell GO:0004308 exo-alpha-sialidase activity GO:0046789 host cell surface receptor binding GO:0016020 membrane GO:0016021 integral component of membrane GO:0019012 virion GO:0019031 viral envelope GO:0033644 host cell membrane \ GO:0016798 hydrolase activity, acting on glycosyl bonds
Organisms for which functions have been demonstratedParamyxovirus (Mumps virus)
Sequence length582
FASTA sequence>tr|B9VJ59|B9VJ59_9MONO HN OS=Mumps rubulavirus PE=3 SV=1 MEPSKLFTISDNATFAPGPVINAADKKTFRTCFRILVLSVQAVTLILVIVTLGELVRMINDQGLSNQLPSITNKIRESATMIASAVGVMNQVIHGVTISLPLQIEGNQNQLLSTLATICTSKKQVSNCSTNIPLVNDLRFINGINKFIIEDYATHDFSIGHPLNMPSFIPTATSPNGCTRIPSFSLGKTHWCYTHNVINANCKDHTSSNQYVSMGILVQTASRYPMFKTLKIQYLSDGLNRKSCSIATVPDGCAMYCYVSTQLETDDYAGSSPPTQKLTLLFYNDTVTERTISPSGLEGNWATLVPGVGSGIYFENKLIFPAYGGVLPNSTLGVKSAREFFRPVNPYNPCSGPQQDLDQRALRSYFPSYFSNRRVQSAFLVCAWNQILVTNCELVVPSSNQTLMGAEGRVLLINNRLLYYQRSTSWWPYELLYEISFTFTNSGQSSVNMSWIPIYSFTRPGSGSCSGENVCPTACVSGVYLDPWPLTPYSHQSGINRNFYFTGALLNSSTTRVNPTLYVSALNNLTVLAPYGTQGLFASYTTTTCFQDTGDASVYCVYIMELASNIVGEFQILPVLTRLTIT
Structure Information
PDB ID1Z4V 1Z4W 1Z4X 1Z4Y 1Z4Z 1Z50
Quaternary structure
Function 1
Function descriptionhemagglutinin binding the virus to the surface of host cells
References for functionCrennell S, Takimoto T, Portner A, Taylor G. Crystal structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase. Nat Struct Biol. 2000 Nov. PMID: 11062565
E.C. numberN/A
Location of functional site(s)
Cellular location of functionsurface of virus
Comments
Function 2
Function descriptionNeuraminidase, enzyme cleaves the glycosidic linkages of neuraminic acids
References for functionCrennell S, Takimoto T, Portner A, Taylor G. Crystal structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase. Nat Struct Biol. 2000 Nov. PMID: 11062565
E.C. number3.2.1.18
Location of functional site(s)
Cellular location of functionsurface of virus
Comments