Protein Information

General Information
MoonProt ID183
First appeared in release1.0
Name(s)40S ribosomal protein S13 Gene Name:RPS13
UniProt IDP62277 (RS13_HUMAN), Reviewed
GO termsGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0006412 translation GO:0006413 translational initiation GO:0006414 translational elongation GO:0006415 translational termination GO:0006614 SRP-dependent cotranslational protein targeting to membrane GO:0010467 gene expression GO:0016032 viral process GO:0016070 RNA metabolic process GO:0016071 mRNA metabolic process GO:0019058 viral life cycle GO:0019083 viral transcription GO:0033119 negative regulation of RNA splicing GO:0044267 cellular protein metabolic process GO:0003729 mRNA binding GO:0003735 structural constituent of ribosome GO:0005515 protein binding GO:0044822 poly(A) RNA binding GO:0005622 intracellular GO:0005634 nucleus GO:0005730 nucleolus GO:0005829 cytosol GO:0005840 ribosome GO:0022627 cytosolic small ribosomal subunit GO:0030529 ribonucleoprotein complex GO:0070062 extracellular vesicular exosome GO:0003723 RNA binding GO:0043484 regulation of RNA splicing
Organisms for which functions have been demonstratedHomo sapiens
Sequence length151
FASTA sequence>sp|P62277|RS13_HUMAN 40S ribosomal protein S13 OS=Homo sapiens GN=RPS13 PE=1 SV=2 MGRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIGVILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKHLERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA
Structure Information
PDB ID3J3A, 4KZX, 4KZY, 4KZZ
Quaternary structure
Function 1
Function descriptionribosomal protein, part of the ribosome
References for functionDieci, Giorgio, et al. "tRNA-assisted overproduction of eukaryotic ribosomal proteins." Protein expression and purification 18.3 (2000): 346-354.
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasm, part of the ribosome
Comments
Function 2
Function descriptioninhibits splicing of own RNA transcript inhibit removal of intron 1 from rpS13 pre-mRNA
References for functionMalygin AA, Parakhnevitch NM, Ivanov AV, Eperon IC, Karpova GG. Human ribosomal protein S13 regulates expression of its own gene at the splicing step by a feedback mechanism. Nucleic Acids Res. 2007 0. PMID: 17881366
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasm
Comments