Protein Information

General Information
MoonProt ID19
First appeared in release1.0
Name(s)DnaK Chaperone protein DnaK HSP70 Heat shock 70 kDa protein Heat shock protein 70 Gene Name: dnaK
UniProt IDP0A3J0 (DNAK_LACLA), Reviewed
GO termsGO:0006457 protein folding GO:0006950 response to stress GO:0000166 nucleotide binding GO:0005524 ATP binding GO:0051082 unfolded protein binding GO: 0005515 protein binding
Organisms for which functions have been demonstratedLactococcus lactis IL1403
Sequence length607
FASTA sequence>gi|15672936|ref|NP_267110.1| molecular chaperone DnaK [Lactococcus lactis subsp. lactis Il1403] MSKIIGIDLGTTNSAVAVLEGTESKIIPNPEGNRTTPSVVAFKNGEIIVGDAAKRQAVTNPETIISIKSKMGTSEKVSANGKEYTPQEISAMILQNLKATAEAYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDKDEKILVFDLGGGTFDVSILELGDGVFDVLATAGNNKLGGDDFDQKIIDWMVAEFKKENGIDLAQDKMALQRLKDAAEKAKKDLSGVTTTQISLPFITAGAAGPLHLEMALTRAKFDELTHDLVEATRQPVRQALSDAGLSTSDIDEVLLVGGSTRIPAVVELVRHETNKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQTIVIKSNSGLSDEEIDKMMKDAEANADADAKRKEEVDTRNEADALVFQTEKTLKDLEGKVEEAEVKKAEEAKEELKKALEGEDIDDIKAKSEALSEIAQNLAVKLYEQANAAQGEAGQATDAQEAPKDDNTFDGDFEESK
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionchaperone
References for functionYuan, Gang, and Sui-Lam Wong. "Isolation and characterization of Bacillus subtilis groE regulatory mutants: evidence for orf39 in the dnaK operon as a repressor gene in regulating the expression of both groE and dnaK." Journal of bacteriology 177.22 (1995): 6462-6468.
E.C. number
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionbinding to invertase, a hyperglycosylated mannoprotein from Saccharomyces cerevisiae
References for functionKatakura Y, Sano R, Hashimoto T, Ninomiya K, Shioya S. 2010. Lactic acid bacteria display on the cell surface cytosolic proteins that recognize yeast mannan. Appl Microbiol Biotechnol. 2010 Mar;86(1):319-26. doi: 10.1007/s00253-009-2295-y. Epub 2009 Nov 7.PMID: 19898842
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface, cell wall
Commentspart of a symbiotic relationship with yeast