Protein Information

General Information
MoonProt ID195
First appeared in release1.0
Name(s)Enolase 2-phospho-D-glycerate hydro-lyase 2-phosphoglycerate dehydratase Gene Name:eno
UniProt IDA8AY46 (ENO_STRGC), Reviewed
GO termsGO:0006096 glycolytic process GO:0000287 magnesium ion binding GO:0004634 phosphopyruvate hydratase activity GO:0016829 lyase activity GO:0046872 metal ion binding GO:0000015 phosphopyruvate hydratase complex GO:0005576 extracellular region GO:0005737 cytoplasm GO:0009986 cell surface GO:0005515 protein binding GO:0098631 cell adhesion mediator activity
Organisms for which functions have been demonstratedStreptococcus gordonii
Sequence length434
FASTA sequence>sp|A8AY46|ENO_STRGC Enolase OS=Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288) GN=eno PE=3 SV=1 MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNVIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDGVETIIAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTAAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLSRGIKEGCANSILIKVNQIGTLTETFDAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGLQAFYNLKK
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionenolase, enzyme Catalyzes the interconversion of 2-phosphoglycerate and phosphoenolpyruvate 2-phospho-D-glycerate <=> phosphoenolpyruvate + H2O Carbohydrate degradation, glycolysis
References for functionKesimer, Mehmet, et al. "Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii." BMC microbiology9.1 (2009): 163.
E.C. number4.2.1.11
Location of functional site(s)Active site:205,343 Binding site:318,164,291,343,155,394 Metal binding site:242,291,318
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionadhesin, binds salivary mucin MUC7
References for functionKesimer M, Kili? N, Mehrotra R, Thornton DJ, Sheehan JK. Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii. BMC Microbiol. 2009 Aug 11. PMID: 19671172
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments