Protein Information

General Information
MoonProt ID229
First appeared in release1.0
Name(s)Enolase 2-phospho-D-glycerate hydro-lyase 2-phosphoglycerate dehydratase Gene Name: eno
UniProt IDC4XEI3
GO termsGO:0006096 glycolytic process GO:0000287 magnesium ion binding GO:0004634 phosphopyruvate hydratase activity GO:0016829 lyase activity GO:0046872 metal ion binding GO:0000015 phosphopyruvate hydratase complex GO:0005576 extracellular region GO:0005737 cytoplasm GO:0009986 cell surface GO:0005515 protein binding
Organisms for which functions have been demonstratedMycoplasma fermentans
Sequence length460 aa
FASTA sequence>tr|C4XEI3|C4XEI3_MYCFP Enolase OS=Mycoplasma fermentans (strain ATCC 19989 / NBRC 14854 / NCTC 10117 / PG18) GN=eno PE=3 SV=1 MKLRRKMSAIYKIHSREILDSRGNPTVQVEVWTEAGGYGLANVPSGASTGSKEALELRDQGTKYEKNWFGGKGVMTAVDHVNKDIAPKLLGMEVTDQRAIDMKMIKLDGTATKSKFGANAILGVSLAVARAAADELQLPLYRYIGGTNAHVLPLPMLNVMNGGAHASNTVDFQEFMIMPVGAKSIREALQMANKVFHNLAKLLKAAGHGTQVGDEGGFAPDCKSHEEVLDYLVQAIKAAGYKPATSGKDAVAIAMDAASSEIYDEKSKKYVFKKLKKAIEAKHPGFEKLTNVKLEYTTDEMIEYYGTLIAKYPIISIEDGLAEDDWAGFTKMTTKYGHQIQIVGDDLTVTNPKLLARAIKEKAMNAILIKLNQIGSLTETIDAINMAQKAGMACVVSHRSGETEDTTLADVAVALNTGQIKTGSMSRTDRIAKYNRLLAIEEELDGADEFEGREAFYNIK
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionenolase, enzyme 2-phospho-D-glycerate <=> phosphoenolpyruvate + H2O Carbohydrate degradation, glycolysis
References for functionIshida, Noriko, et al. "Molecular cloning and expression of a novel cholinephosphotransferase involved in glycoglycerophospholipid biosynthesis of Mycoplasma fermentans." Current microbiology 58.6 (2009): 535-540.
E.C. number4.2.1.11
Location of functional site(s)binding site: 165, 174, 318, 345, 370, 421; active site: 215, 370; metal binding: 345
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionplasminogen binding
References for functionYavlovich A, Rechnitzer H, Rottem S. Alpha-enolase resides on the cell surface of Mycoplasma fermentans and binds plasminogen. Infect Immun. 2007 Dec. PMID: 17938226
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments