Protein Information

General Information
MoonProt ID23
First appeared in release1.0
Name(s)Ef-Tu Elongation factor Tu Gene Name: tuf
UniProt IDP23568 (EFTU_MYCPN), Reviewed
GO termsGO:0006184 GTP catabolic process GO:0006412 translation GO:0006414 translational elongation GO:0000166 nucleotide binding GO:0003746 translation elongation factor activity GO:0003924 GTPase activity GO:0005525 GTP binding GO:0005622 intracellular GO:0005737 cytoplasm GO: 0098631 cell adhesion mediator activity GO: 0005515 protein binding
Organisms for which functions have been demonstratedMycoplasma pneumoniae
Sequence length394
FASTA sequence>sp|P23568|EFTU_MYCPN Elongation factor Tu OS=Mycoplasma pneumoniae (strain ATCC 29342 / M129) GN=tuf PE=3 SV=2 MAREKFDRSKPHVNVGTIGHIDHGKTTLTAAICTVLAKEGKSAATRYDQIDKAPEEKARGITINSAHVEYSSDKRHYAHVDCPGHADYIKNMITGAAQMDGAILVVSATDSVMPQTREHILLARQVGVPRMVVFLNKCDIATDEEVQELVAEEVRDLLTSYGFDGKNTPIIYGSALKALEGDPKWEAKIHDLMNAVDEWIPTPEREVDKPFLLAIEDTMTITGRGTVVTGRVERGELKVGQEIEIVGLRPIRKAVVTGIEMFKKELDSAMAGDNAGVLLRGVDRKEVERGQVLAKPGSIKPHKKFKAEIYALKKEEGGRHTGFLNGYRPQFYFRTTDVTGSISLPENTEMVLPGDNTSITVELIAPIACEKGSKFSIREGGRTVGAGSVTEVLE
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionelongation factor in protein synthesis during protein biosynthesis: promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes
References for functionDallo, Shatha F., et al. "Elongation factor Tu and E1 beta subunit of pyruvate dehydrogenase complex act as fibronectin binding proteins in Mycoplasma pneumoniae." Molecular microbiology46.4 (2002): 1041-1051.
E.C. numberN/A
Location of functional site(s)Nucleotide binding site:19-26,136-139,81-85
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionfibronectin binding
References for functionDallo SF, Kannan TR, Blaylock MW, Baseman JB. Elongation factor Tu and E1 beta subunit of pyruvate dehydrogenase complex act as fibronectin binding proteins in Mycoplasma pneumoniae. Mol Microbiol. 2002 Nov;46(4):1041-51. PMID: 12421310
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments