Protein Information

General Information
MoonProt ID247
First appeared in release1.0
Name(s)30S ribosomal protein S4 Gene Name: rpsD
UniProt IDP0A7V8 (RS4_ECOLI), Reviewed
GO termsGO:0006351 transcription, DNA-templated GO:0006353 DNA-templated transcription, termination GO:0006355 regulation of transcription, DNA-templated GO:0006412 translation GO:0006417 regulation of translation GO:0031564 transcription antitermination GO:0045947 negative regulation of translational initiation GO:0046677 response to antibiotic GO:0000900 translation repressor activity, nucleic acid binding GO:0003723 RNA binding GO:0003735 structural constituent of ribosome GO:0019843 rRNA binding GO:0048027 mRNA 5'-UTR binding GO:0005622 intracellular GO:0005840 ribosome GO:0015935 small ribosomal subunit GO:0022627 cytosolic small ribosomal subunit GO:0030529 ribonucleoprotein complex GO:0003723 RNA binding GO:0006412 translation GO:0003729 mRNA binding
Organisms for which functions have been demonstratedEscherichia coli
Sequence length206
FASTA sequence>sp|P0A7V8|RS4_ECOLI 30S ribosomal protein S4 OS=Escherichia coli (strain K12) GN=rpsD PE=1 SV=2 MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK
Structure Information
PDB ID 1VS5, 1VS7, 3E1A, 3E1C, 3I1M, 3I1O, 3I1Q, 3I1S, 3I1Z, 3I21, 3KC4, 3OR9, 3ORA, 3IZV, 3IZW, 3SFS, 3UOQ, 4GAQ, 4GAS, 4KIY, 4KJ0, 4KJ2, 4KJ4, 4KJ6, 4KJ8, 4KJA, 4KJC, 3J4V, 3J4W, 3J4Y, 3J4Z, 3J53, 1P87, 2AVY, 2AW7, 2I2P, 2I2U, 2QOU, 2QOW, 2QOY, 2OP0, 2QAL 2QA
Quaternary structure
Function 1
Function descriptionS4 ribosomal protein part of the 30S subunit, helps nucleate assembly of the 30S subunit by binding directly to the 16S rRNA
References for functionReinbolt, J., and E. Schiltz. "The primary structure of ribosomal protein S4 from Escherichia coli." FEBS letters 36.3 (1973): 250-252.
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptiontranslational repressor binds mRNA of operon encoding S3, S11, S4
References for functionYates JL, Arfsten AE, Nomura M. In vitro expression of Escherichia coli ribosomal protein genes: autogenous inhibition of translation. Proc Natl Acad Sci U S A. 1980 Apr. PMID: 6445562
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasm
Comments