Protein Information

General Information
MoonProt ID261
First appeared in release1.0
Name(s)Autolysin AtlA Gene Name:atlA
UniProt IDU3SW74 (U3SW74_STRMG), Unreviewed
GO termsGO:0005975 carbohydrate metabolic process GO:0009253 peptidoglycan catabolic process GO:0016998 cell wall macromolecule catabolic process GO:0005515 protein binding GO:0098631 cell adhesion mediator GO:0003796 lysozyme activity
Organisms for which functions have been demonstratedStreptococcus mutans
Sequence length979
FASTA sequence>tr|U3SW74|U3SW74_STRMG Autolysin AtlA OS=Streptococcus mutans LJ23 GN=atlA PE=4 SV=1 MKSKTYLMIPLALTLFMAANKISADEQNQSLSASEVISSDATSVSELPATTAQISQEVRNNGQDSTIQLQQTQEQSDPITSTSETTVSSMKVATNGSPAKANETETVPSQASTASSVQTPDQISTVPSVKAETTSTADQLQSTSSAPLDQQTDAKRLSNKMTPASSVQARSSLTQDKQVQAQEVTSAVVEEKGIKLQYNGQIARNTKIQFAVWSARNDQDDLQWYTANNMGAAYAEFKNHREYGTYYVHTYANQNGKMIGLNATTLTIAQPQVQTNIQRKSATNFELTVSNVPNTISSIMVPVWSDQNGQDDIKWYNARKADDGSYKVLIDTKNHKNDLGHYEAHIYGYSTVTQSQIGLAVSSGFDRNDTRPNARISVANYDQNKTTFDVVVEGSSDTKTVSAVNIAVWSEDKGQDDLKWYSPKIVNNKATVTINIANHSNTSDKYNVHVYTDYTDGTHSGTILGAYQINKPLEKNTVSADLTSDGIALKLDSNTVTDYTKVRFAVWSDQNGQDDLKWYSANSDGAATAAYSNHSGYGLYHIHTYIIKDGKMVGLNGRTITINQPSAKVDIAKESDALYKVTVSNLPAYISSVVIPVWTDKNNQDDIQWIPATKQGDGTYAAQIQLADHNGETGHYNVHVYGQSKFDNKTVGLAATDGFNVAETRNAVIAASNYNASAGTIDMIVKQEAGGKAIKEVRIAAWSEADQSNLHWYVSSTIIDGKVTVTINEKNHQYIKGNYNIHVYVDYTDGTSSGTNIGNYSLNADKPAVDLPSYFIDISSHNGIISVAEFNSLKQQGIQGVVVKLTEGTSYINPYASSQIANARAAGIKVSAYHYAHYTSAAEAQEEARYFANAARSFGLEASTVTVNDMEESSMVNNINNNVQAWQDEMRRQGYSNLIHYTMASWLDIRGGQVDTARFGINNFWVAHYAKGYTYMTQEEAKSLNYYANAAAWQYTSVSSKLSHALDENIDYTGRFTQQ
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionautolysin, enzyme cleaves cell wall peptidoglycan
References for functionTamura, Haruki, et al. "Identification and characterization of an autolysin gene, atlh, from Streptococcus downei." Current microbiology 58.5 (2009): 432-437.
E.C. number3.5.1.28
Location of functional site(s)
Cellular location of functioncell surface
Comments
Function 2
Function descriptionbinds fibronectin
References for functionJung CJ, Zheng QH, Shieh YH, Lin CS, Chia JS. Streptococcus mutans autolysin AtlA is a fibronectin-binding protein and contributes to bacterial survival in the bloodstream and virulence for infective endocarditis. Mol Microbiol. 2009 Nov;74(4):888-902. doi: 10.1111/j.1365-2958.2009.06903.x. PMID: 19818020
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments