Protein Information

General Information
MoonProt ID31
First appeared in release1.0
Name(s)Enolase Enolase 1 2-phospho-D-glycerate hydro-lyase 1 2-phosphoglycerate dehydratase 1 enoA, enoA1 alfa-enolase Gene Name: eno1
UniProt IDQ88YH3 (ENO1_LACPL), Reviewed
GO termsGO:0006096 glycolysis GO:0000287 magnesium ion binding GO:0004634 phosphopyruvate hydratase activity GO:0016829 lyase activity GO:0046872 metal ion binding GO:0000015 phosphopyruvate hydratase complex GO:0005576 extracellular region GO:0005737 cytoplasm GO:0009986 cell surface GO: 0098631 cell adhesion mediator activity GO: 0005515 protein binding
Organisms for which functions have been demonstratedLactobacillus plantarum
Sequence length442
FASTA sequence>sp|Q88YH3|ENO1_LACPL Enolase 1 OS=Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) GN=eno1 PE=3 SV=1 MSIITDIYAREVLDSRGNPTVEVELYTESGAFGRGIVPSGASTGEHEAVELRDGDKSRFMGKGVTKAVDNVNKLIAKEIVGYDVTDQRAIDQAMIKLDGTPNKAKLGANAILGVSIAAARAAADELEMPLYNYLGGFNAHVLPTPMMNVINGGAHANNDVDFQEFMIMPVGASSVKEAIRMGSETFHNLKAILNERGYSTAVGDEGGFAPDLKNNEEPFEILVEAIERAGYKPGKDIAIAFDCAASEFYNEETGKYDLKGEGENGQSFTAEEFVDLLDSIVDKYPIVSIEDPLDENNWEDWQMATAKLGKKVQIVGDDLFVTNTDYLAKGIKMGVANSILIKVNQIGTLTETVEAIEMAKEAGYTAIVSHRSGETEDTTIADLVVAMNAGQIKTGSMSRTERIAKYNQLMRIEDQLESTSEYKGIHGFYNLDEAARNTITSK
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionEnolase, enzyme 2-phospho-D-glycerate => phosphoenolpyruvate + H2O Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate Carbohydrate degradation, glycolysis
References for functionHao, Zhiqi, Shaolin Chen, and David B. Wilson. "Cloning, expression, and characterization of cadmium and manganese uptake genes from Lactobacillus plantarum." Applied and environmental microbiology 65.11 (1999): 4746-4752.
E.C. number4.2.1.11
Location of functional site(s)Active site:205,342 Binding site:290,164,393,155,317,342 Metal binding site:317,242,290
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionbinds fibronectin
References for functionCastaldo C, Vastano V, Siciliano RA, Candela M, Vici M, Muscariello L, Marasco R, Sacco M. Surface displaced alfa-enolase of Lactobacillus plantarum is a fibronectin binding protein. Microb Cell Fact. 2009 Feb 16;8:14.doi: 10.1186/1475-2859-8-14. PMID: 19220903
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments