Protein Information

General Information
MoonProt ID32
First appeared in release1.0
Name(s)Enolase 2-phospho-D-glycerate hydro-lyase 2-phosphoglycerate dehydratase Gene Name: eno
UniProt IDE0N8L2 (E0N8L2_NEIME), Unreviewed
GO termsGO:0006096 glycolysis GO:0000287 magnesium ion binding GO:0004634 phosphopyruvate hydratase activity GO:0016829 lyase activity GO:0046872 metal ion binding GO:0000015 phosphopyruvate hydratase complex GO:0005576 extracellular region GO:0005737 cytoplasm GO:0009986 cell surface GO: 0005515 protein binding
Organisms for which functions have been demonstratedNeisseria meningitidis
Sequence length428
FASTA sequence>gi|488142178|ref|WP_002213386.1| enolase [Neisseria meningitidis] MSAIVDIFAREILDSRGNPTVECDVLLESGVMGRAAVPSGASTGQKEALELRDGDKSRYSGKGVLKAVEHVNNQIAQALIGIDANEQSYIDQIMIELDGTENKGNLGANATLAVSMAVARAAAEDSGLPLYRYLGGAGPMSLPVPMMNVINGGEHANNSLNIQEFMIMPVGAKSFREALRCGAEIFHALKKLCDSKGFPTTVGDEGGFAPNLNSHKEALQLMVEATEAVGYKAGEDVLFALDCASSEFYKDGKYHLEAEGRSYTNAEFAEYLESLVNEFPIISIEDGMDENDWEGWKLLTEKLGGKVQLVGDDLFVTNPKILAEGIEKGVANALLVKVNQIGTLSETLKAVDLAKRNRYASVMSHRSGETEDSTIADLAVATNCMQIKTGSLSRSDRMAKYNQLLRIEEELAEAAYYPGKAAFYQLGK
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionEnolase 2-phospho-D-glycerate => phosphoenolpyruvate + H2O. Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate Carbohydrate degradation, glycolysis
References for function1st function reference: Jyssum, K., Björg Borchgrevink, and Sidsel Jyssum. "GLUCOSE CATABOLISM IN NEISSERIA MENINGITIDIS." APMIS 53.1 (1961): 71-83.
E.C. number4.2.1.11
Location of functional site(s)Active site:205,337 Binding site:164,388,285,155,312,337 Metal binding site:242,312,285
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionplasminogen binding
References for functionKnaust A, Weber MV, Hammerschmidt S, Bergmann S, Frosch M, Kurzai O. (2007) Cytosolic proteins contribute to surface plasminogen recruitment of Neisseria meningitidis. J Bacteriol. 189(8):3246-55.Epub 2007 Feb 16. PMID: 17307854
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments