Protein Information

General Information
MoonProt ID321
First appeared in release2.0
Name(s)elongation factor 1alpha, EF-1alpha, Elongation factor 1-alpha 1, EF-1-alpha-1, Elongation factor Tu, EF-Tu, Eukaryotic elongation factor 1 A-1, eEF1A-1, Gene: EEF1A1
UniProt IDP68105 (EF1A1_RABIT)
GO termsGO:0006412 translation GO:0006414 translational elongation GO:0071364 cellular response to epidermal growth factor stimulus GO:0000049 tRNA binding GO:0000166 nucleotide binding GO:0003746 translation elongation factor activity GO:0003924 GTPase activity GO:0005515 protein binding GO:0005525 GTP binding GO:0019001 guanyl nucleotide binding GO:0019901 protein kinase binding GO:0044822 poly(A) RNA binding GO:0005615 extracellular space GO:0005634 nucleus GO:0005730 nucleolus GO:0008017 microtubule binding GO:0051013 microtubule servering GO:0005515 protein binding
Organisms for which functions have been demonstratedOryctolagus cuniculus (rabbit)
Sequence length462 amino acids
FASTA sequence>sp|P68105|EF1A1_RABIT Elongation factor 1-alpha 1 OS=Oryctolagus cuniculus GN=EEF1A1 PE=1 SV=1 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPP
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptiontranslation elongation factor
References for functionDever, Thomas E., et al. "Location of seven post-translational modifications in rabbit elongation factor 1 alpha including dimethyllysine, trimethyllysine, and glycerylphosphorylethanolamine." Journal of Biological Chemistry264.34 (1989): 20518-20525.
E.C. number
Location of functional site(s)nucleotide binding: 14-21, 91-95, 153-156
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionbinds and severs microtubules
References for function7939665
E.C. number
Location of functional site(s)
Cellular location of functioncytoplasm
Comments