Protein Information

General Information
MoonProt ID323
First appeared in release2.0
Name(s)Ef-Tu, translation elongation factor Tu, Gene: tuf
UniProt IDA8AWA0 (EFTU_STRGC)
GO termsGO:0006412 translation GO:0006414 translational elongation GO:0000166 nucleotide binding GO:0003746 translation elongation factor activity GO:0003924 GTPase activity GO:0005525 GTP binding GO:0005622 intracellular GO:0005737 cytoplasm GO:0005515 protein binding
Organisms for which functions have been demonstratedStreptococcus gordonii
Sequence length398 amino acids
FASTA sequence>sp|A8AWA0|EFTU_STRGC Elongation factor Tu OS=Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288) GN=tuf PE=3 SV=1 MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMDLMNTVDEYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEEIQKAVVTGVEMFRKQLDEGLAGDNVGVLLRGIQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTIEVELIHPIAVEQGTTFSIREGGRTVGSGMVTEIEA
Structure Information
PDB IDnone, closest homologue has 70% amino acid sequence identity
Quaternary structure
Function 1
Function descriptiontranslation elongation factor Tu
References for functionLandini, Paolo, et al. "Sensitivity of elongation factor Tu (EF-Tu) from different bacterial species to the antibiotics efrotomycin, pulvomycin and MDL 62879." Microbiology 139.4 (1993): 769-774.
E.C. number
Location of functional site(s)nucleotide binding: 19-26, 84-88, 139-142
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionMucin (MUC7)-binding protein
References for functionKesimer M, Kilic¸ N, Mehrotra R, Thornton DJ, Sheehan JK. (2009) Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii. BMC Microbiol. 9, 163. PMID: 19671172
E.C. number
Location of functional site(s)
Cellular location of functioncell surface
Comments