Protein Information

General Information
MoonProt ID341
First appeared in release2.0
Name(s)GAPDH, glyceraldehyde-3-phosphate dehydrogenase, Gene: LBS0698
UniProt IDQ5FL51 (Q5FL51_LACAC)
GO termsGO:0006096 glycolytic process GO:0005515 protein binding
Organisms for which functions have been demonstratedLactobacillus acidophilus
Sequence length338 amino acids
FASTA sequence>tr|Q5FL51|Q5FL51_LACAC Glyceraldehyde-3-p dehydrogenase OS=Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) GN=LBA0698 PE=3 SV=1 MTVKIGINGFGRIGRLAFRRIMDLGEKSKDIEVVAINDLTTPALLAHLLKYDSTHGTFDHEVSSTEDSIVVDGKKYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGVKRVLISAPAGNDLKTIVYSVNQDTLTADDKIVSAGSCTTNSLAPMVNALQKEFGIEVGTMTTIHAYTSTQMILDGPVRGGNLRAARAAAINIIPHSTGAAKAIGLVIPELNGKLNGHAQRVPVPDGSVTELVSILGKNVTADEVNEAMKKYESPSFEYEPNNVVSSDILGRTAGSIFDPTQTMVTTAGDKQLVKTVAWYDNEYSFTCQMVRTLLHFATL
Structure Information
PDB ID
Quaternary structuretetramer
Function 1
Function descriptionglyceraldehyde-3-phosphate dehydrogenase, enzyme in glycolysis, oxidative phosphorylation of G3P (glyceraldehyde 3-phosphate) to 1, 3-bisphosphoglycerate in the presence ofNADH/NADPH and inorganic phosphate
References for functionPatel, Dhaval K., et al. "Cloning, expression and characterization of a mucin-binding GAPDH from Lactobacillus acidophilus." International journal of biological macromolecules 91 (2016): 338-346.
E.C. number1.2.1.12
Location of functional site(s)active site: 156; site: 183; binding site: 186, 239
Cellular location of functionintracellular
CommentsL. acidophilus is considered a commensual bacterium, used in probiotics, colonizes the gut
Function 2
Function descriptionmucin binding
References for function27180300
E.C. number
Location of functional site(s)
Cellular location of functioncell surface
Comments