Protein Information

General Information
MoonProt ID35
First appeared in release1.0
Name(s)Enolase 2-phospho-D-glycerate hydro-lyase 2-phosphoglycerate dehydratase Gene Name: eno
UniProt IDA0A1F1EC06
GO termsGO:0006096 glycolysis GO:0000287 magnesium ion binding GO:0004634 phosphopyruvate hydratase activity GO:0016829 lyase activity GO:0046872 metal ion binding GO:0000015 phosphopyruvate hydratase complex GO:0005576 extracellular region GO:0005737 cytoplasm GO:0009986 cell surface GO:0005515 protein binding
Organisms for which functions have been demonstratedEnolase, Oral streptococci (S. anginosus, S. oralis)
Sequence length434
FASTA sequence>tr|A0A1F1EC06|A0A1F1EC06_9STRE Enolase OS=Streptococcus sp. HMSC071H03 GN=eno PE=3 SV=1 MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAVIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIVNGGSHSDAPIAFQEFMIVPAGAPTFKEALRWGAEIFHTLKKILKSRGLETAVGDEGGFAPRFDGTEDGVETILAAIEAAGYVPGKDVFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTADEQIEYLEQLVDKYPIITIEDGMDENDWEGWKKLTERLGKKVQLVGDDFFVTNTSYLERGINEGCANSILIKVNQIGTLTETFDAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLSK
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionEnolase, enzyme 2-phospho-D-glycerate => phosphoenolpyruvate + H2O Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate Carbohydrate degradation, glycolysis
References for functionCarlsson, J., Y. Iwami, and T. Yamada. "Hydrogen peroxide excretion by oral streptococci and effect of lactoperoxidase-thiocyanate-hydrogen peroxide." Infection and Immunity 40.1 (1983): 70-80.
E.C. number4.2.1.11
Location of functional site(s)Active site:205,343 Binding site:318,164,291,343,155,394 Metal binding site:242,291,318
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionplasminogen binding
References for functionKinnby B, Booth NA, Svensater G. Plasminogen binding by oral streptococci from dental plaque and inflammatory lesions. Microbiology. 2008 Mar;154(Pt 3):924-31. doi: 10.1099/mic.0.2007/013235-0. 18310038
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments