Protein Information

General Information
MoonProt ID388
First appeared in release2.0
Name(s)RPT5B, 26S protease regulatory subunit 6A homolog B, 26S proteasome AAA-ATPase subunit RPT5b, Proteasome 26S subunit 6A homolog B, Regulatory particle triple-A ATPase subunit 5b, Tat-binding protein 1 homolog B, TBP-1 homolog B, Gene: RPT5B
UniProt IDO04019 (PS6AB_ARATH)
GO termsGO:0009553 embryo sac development GO:0009555 pollen development GO:0010255 glucose mediated signaling pathway GO:0010498 proteasomal protein catabolic process GO:0030163 protein catabolic process GO:0030433 ER-associated ubiquitin-dependent protein catabolic process GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly GO:1901800 positive regulation of proteasomal protein catabolic process GO:0000166 nucleotide binding GO:0005524 ATP binding GO:0016787 hydrolase activity GO:0017025 TBP-class protein binding GO:0036402 proteasome-activating ATPase activity GO:0000502 proteasome complex GO:0005634 nucleus GO:0005737 cytoplasm GO:0005886 plasma membrane GO:0008540 proteasome regulatory particle, base subcomplex GO:0016020 membrane GO:0031595 nuclear proteasome complex GO:0031597 cytosolic proteasome complex GO:0005515 protein binding
Organisms for which functions have been demonstratedArabidopsis thaliana
Sequence length423 amino acids
FASTA sequence>sp|O04019|PS6AB_ARATH 26S protease regulatory subunit 6A homolog B OS=Arabidopsis thaliana GN=RPT5B PE=1 SV=3 MATAMAEDTSFEGDQLASMTTDDIGRASRLLANEIRILKEESQRTNLDLESVKEKIKENQEKIKLNKQLPYLVGNIVEILEMSPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDTLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKEQFEKLGIRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFLLAKEKSPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDDRIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARGRILQIHSRKMNVNADVNFEELARSTDDFNGAQLKAVCVEAGMLALRRDATEVNHEDFNEGIIQVQAKKKASLNYYA
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionpart of the regulatory ATPase complex of the 26S proteasome, confers substrate specificity and need for ATP to the proteaseome
References for functionGallois, Jean-Luc, et al. "The Arabidopsis proteasome RPT5 subunits are essential for gametophyte development and show accession-dependent redundancy." The Plant Cell 21.2 (2009): 442-459.
E.C. number
Location of functional site(s)nucleotide binding: 211-218
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionbinds to hexokinase 1 and VHA B1 to modulate transcription of specific target genes
References for function17081979
E.C. number
Location of functional site(s)
Cellular location of functionnucleus
Comments