Protein Information

General Information
MoonProt ID396
First appeared in release2.0
Name(s)VHA-B1, V-type proton ATPase subunit B1, Gene: VHA-B1
UniProt IDP11574 (VATB1_ARATH)
GO termsGO:0006810 transport GO:0006811 ion transport GO:0010255 glucose mediated signaling pathway GO:0015991 ATP hydrolysis coupled proton transport GO:0015992 proton transport GO:0030835 negative regulation of actin filament depolymerization GO:0046034 ATP metabolic process GO:0046686 response to cadmium ion GO:0051017 actin filament bundle assembly GO:0051693 actin filament capping GO:0005524 ATP binding GO:0016787 hydrolase activity GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances GO:0051015 actin filament binding GO:0005773 vacuole GO:0005774 vacuolar membrane GO:0005794 Golgi apparatus GO:0005886 plasma membrane GO:0009506 plasmodesma GO:0009507 chloroplast GO:0016020 membrane GO:0033180 proton-transporting V-type ATPase, V1 domain GO:0005829 cytosol GO:0005515 protein binding
Organisms for which functions have been demonstratedArabidopsis thaliana
Sequence length486 amino acids
FASTA sequence>sp|P11574|VATB1_ARATH V-type proton ATPase subunit B1 OS=Arabidopsis thaliana GN=VHA-B1 PE=2 SV=2 MGTNDLDIEEGTLEIGMEYRTVSGVAGPLVILDKVKGPKYQEIVNIRLGDGSTRRGQVLEVDGEKAVVQVFEGTSGIDNKFTTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGISTIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEKTVDLLEDHGEDNFAIVFAAMGVNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGRKGSITQIPILTMPNDDITHPTPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYANYAIGKDVQAMKAVVGEEALSSEDLLYLEFLDKFERKFVMQGAYDTRNIFQSLDLAWTLLRIFPRELLHRIPAKTLDQFYSRDSTS
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionsubunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase functions in acidifying several intracellular compartments in eukaryotic cells
References for functionManolson, Morris F., et al. "cDNA sequence and homologies of the" 57-kDa" nucleotide-binding subunit of the vacuolar ATPase from Arabidopsis." Journal of Biological Chemistry 263.34 (1988): 17987-17994.
E.C. number
Location of functional site(s)
Cellular location of functionmembrane
Comments
Function 2
Function descriptionbinds to hexokinase 1 and the 19S regulatory particle of proteasome subunit (RPT5B) to modulate transcription of specific target genes
References for function17081979
E.C. number
Location of functional site(s)
Cellular location of functionnucleus
Comments