Protein Information

General Information
MoonProt ID43
First appeared in release1.0
Name(s)enolase Gene Name: ENO
UniProt IDQ3HL75 (Q3HL75_LEIME), Unreviewed
GO termsGO:0006096 glycolysis GO:0000287 magnesium ion binding GO:0004634 phosphopyruvate hydratase activity GO:0016829 lyase activity GO:0000015 phosphopyruvate hydratase complex GO:0005515 protein binding
Organisms for which functions have been demonstratedLeishmania mexicana
Sequence length429
FASTA sequence>gi|77176833|gb|ABA64522.1| enolase [Leishmania mexicana] MPILKIHAREVLDSRGNPTVEVELTTEAGVFRSAVPSGASTGVHEACELRDGDKARYCGAGCTQAVKYVNEILAPALVGKDESDQAGLDKLMCELDGTKNKSKLGANAILGCSMAISKAAAAKAGVPLYRYIAGLAGTKDMRLPVPCFNVINGGKHAGNVLPFQEFMIAPTKATSFREALRMGSEVYHALKGIIKGKYGQDAVNVGDEGGFAPPIKQIDEPLPILMEAIEKAGHKGKFAICMDCAASEAYDAERKMYNLTFKNPEPTYVSAAKLQETYERWVSEYPLVSIEDPFAEDNFDEFSAITKALAGKAQIVGDDLTVTNVERVKMAIDKSACNSLLLKINQIGTISESIAAAKLCMENGWSVMVSHRSGETEDTYIADLSVGLGTGQIKTGAPCRGERTAKLNQLLRIEEEMGSAAKYGYPGWA
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionenolase, enzyme reversible conversion of 2-phosphoglycerate to phosphoenolpyruvate
References for functionHannaert, VĂ©ronique, et al. "Molecular analysis of the cytosolic and glycosomal glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicana." Molecular and biochemical parasitology55.1-2 (1992): 115-126.
E.C. number4.2.1.11
Location of functional site(s)Active site:208,343 Binding site:318,291,156,165,394
Cellular location of functioncytosol
Comments
Function 2
Function descriptionbinds plasminogen
References for functionVanegas G, Qui?ones W, CarrascoL?pez C, Concepci?n JL, Albericio F, Avil?n L. Enolase as a plasminogen binding protein in Leishmania mexicana. Parasitol Res. 2007 Nov;101(6):1511-6. Epub 2007 Jul 27. PMID: 17653767
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments