Protein Information

General Information
MoonProt ID45
First appeared in release1.0
Name(s)enolase ?-enolase 2-phospho-D-glycerate hydrolase 2-phosphoglycerate dehydratase Gene Name: eno
UniProt IDD8H2L1 (D8H2L1_BACAI), Unreviewed
GO termsGO:0006096 glycolysis GO:0000287 magnesium ion binding GO:0004634 phosphopyruvate hydratase activity GO:0016829 lyase activity GO:0046872 metal ion binding GO:0000015 phosphopyruvate hydratase complex GO:0005576 extracellular region GO:0005737 cytoplasm GO:0009986 cell surface GO:0098631 cell adhesion mediator GO:0005515 protein binding
Organisms for which functions have been demonstratedBacillus anthracis
Sequence length431
FASTA sequence>gi|59797626|sp|Q81X78.1|ENO_BACAN RecName: Full=Enolase; AltName: Full=2-phospho-D-glycerate hydro-lyase; AltName: Full=2-phosphoglycerate dehydratase MSTIIDVYAREVLDSRGNPTVEVEVYTESGAFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVMNAVNNVNEAIAPEIVGFDVTDQAGIDRAMIELDGTPNKGKLGANAILGVSMAVAHAAADFVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNVDFQEFMILPVGAPTFKESIRMGAEVFHALKAVLHDKGLNTAVGDEGGFAPNLGSNREALEVIIEAIEKAGYKAGENVFLGMDVASSEFYNKETGKYDLAGEGRTGLTSAEMVDFYEELCKDFPIISIEDGLDENDWDGHKLLTERIGDKVQLVGDDLFVTNTQKLAEGIEKGISNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDRIAKYNQLLRIEDELGEIAVYDGIKSFYNIKR
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionenolase, enzyme 2-phospho-D-glycerate => phosphoenolpyruvate + H2O Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate Carbohydrate degradation, glycolysis
References for functionAmelunxen, Remi, and Marilyn Lins. "Comparative thermostability of enzymes from Bacillus stearothermophilus and Bacillus cereus." Archives of biochemistry and biophysics 125.3 (1968): 765-769.
E.C. number4.2.1.11
Location of functional site(s)Active site:205,340 Binding site:164,288,391,155,340,315 Metal binding site:242,288,315
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionbinds plasminogen and laminin
References for functionAgarwal S, Kulshreshtha P, Bambah Mukku D, Bhatnagar R: Alpha-enolase binds to human plasminogen on the surface of Bacillus anthracis. Biochim Biophys Acta. 2008 Jul-Aug;1784(7-8):986-94. doi: 10.1016/j.bbapap.2008.03.017. Epub 2008 Apr 16. PMID: 18456007
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments