Protein Information

General Information
MoonProt ID49
First appeared in release1.0
Name(s)GAPDH Glyceraldehyde 3-phosphate dehydrogenase Gene Name: gapB
UniProt IDF9UM10 (F9UM10_LACPL), Unreviewed
GO termsGO:0006006 glucose metabolic process GO:0055114 oxidation-reduction process GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity GO:0016491 oxidoreductase activity GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0050661 NADP binding GO:0051287 NAD binding GO:0098631 cell adhesion mediator GO:0005515 protein binding
Organisms for which functions have been demonstratedLactobacillus plantarum
Sequence length340
FASTA sequence>gi|334089837|gb|AEG64641.1| glyceraldehyde-3-phosphate dehydrogenase [Lactobacillus plantarum] MSVKIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNADVSATDDSIVVNGKNYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAKRVLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNCLAPLAFFENKEFGIKVGTMTTIHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRVGVVDGSLTELVAILDKKVTADEVNAAIKKHTEGNESFGYNDDEIVSSDVIGTTFGSIFDPTQTEVTSDGDNQLVKTVAWYDNEYGFTCQMVRTLLKFATL
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionGAPDH, enzyme Glyceraldehyde 3-phosphate dehydrogenase
References for functionHao, Zhiqi, Shaolin Chen, and David B. Wilson. "Cloning, expression, and characterization of cadmium and manganese uptake genes from Lactobacillus plantarum." Applied and environmental microbiology 65.11 (1999): 4746-4752.
E.C. number1.2.1.12
Location of functional site(s)Active site:156 Binding site:186,239 Other functional site:183
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionbinds mucin and Caco-2 cells
References for functionKinoshita H, Uchida H, Kawai Y, Kawasaki T, Wakahara N, Matsuo H,Watanabe M, Kitazawa H, Ohnuma S, Miura K, et al: Cell surface Lactobacillus plantarum LA 318 glyceraldehyde-3-phosphate dehydrogenase (GAPDH) adheres to human colonic mucin.J Appl Microbiol. 2008 Jun;104(6):1667-74. doi: 10.1111/j.1365-2672.2007.03679.x. Epub 2008 Jan 9. PMID: 18194256
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments