Protein Information

General Information
MoonProt ID52
First appeared in release1.0
Name(s)GAPDH Glyceraldehyde-3-phosphate dehydrogenase
UniProt IDA0A0F2E7M6
GO termsGO:0006006 glucose metabolic process GO:0055114 oxidation-reduction process GO:0016491 oxidoreductase activity GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0050661 NADP binding GO:0051287 NAD binding GO:0005515 protein binding
Organisms for which functions have been demonstratedOral streptococci (S. anginosus and S. oralis)
Sequence length149 aa
FASTA sequence>tr|A0A0F2E7M6|A0A0F2E7M6_STROR Glyceraldehyde-3-phosphate dehydrogenase OS=Streptococcus oralis subsp. tigurinus GN=gapA PE=3 SV=1 MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWANDGVEIVLEATGFFATKAAAEKHLKGGAKKVVITAPGGSDVKTIVFNTNHDTLDGTETVISGASCTTNCLAPMAKALHDNFGIVEGLMTTIHAYTGDQMILDGPHRKGDLRRARAAAVNIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPAGSVTELVAVLDKNVTVDEVNAAMKAASNESYGYTEDPIVSSDILGMSFGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTSQLVRTLEYFAKIAK
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionGAPDH, Glyceraldehyde-3-phosphate dehydrogenase, enzyme
References for function
E.C. number1.2.1.12
Location of functional site(s)Active site:151 Binding site:181,234 Other functional site:178
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionplasminogen binding
References for functionKinnby B, Booth NA, Svensater G. Plasminogen binding by oral streptococci from dental plaque and inflammatory lesions. Microbiology. 2008 Mar;154(Pt 3):924-31. doi: 10.1099/mic.0.2007/013235-0. PMID: 18310038
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments