Protein Information

General Information
MoonProt ID55
First appeared in release1.0
Name(s)GAPDH Glyceraldehyde-3-phosphate dehydrogenase
UniProt IDQ27820 (Q27820_TRIVA), Unreviewed
GO termsGO:0006006 glucose metabolic process GO:0055114 oxidation-reduction process GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity GO:0016491 oxidoreductase activity GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0050661 NADP binding GO:0051287 NAD binding GO:0098631 cell adhesion mediator GO:0005515 protein binding
Organisms for which functions have been demonstratedTrichomonas vaginalis
Sequence length350
FASTA sequence>gi|432487|gb|AAA30325.1| glyceraldehyde 3-phosphate dehydrogenase, partial [Trichomonas vaginalis] RIGRLVFRACRKLYPKDIQVVAIHDLGDIKTNVYLLKYDTAHRAFPEPVTVDEAKQEFTVGEGADKWVVKSIGGRLGPSQLPWKELGIDVVLESTGIFRTKAEKDAEGKIKKDGYDGHLVSGAKKVVLSVPSADEIECTLVLGVNDEDLKPETKCISNASCTTNCLGPVAKTLNNAFGIRNGFMTTVHSYTNDQVVADTMHKDLRRARAAGMNIIPTSTGAAIALPKVCHGLPPKSLDGFALRVPTITGSLVDLTVNVNAKVTKEEVNAALKKATEEGSLKGIMTYVTDPIVSSDIIGCQYSSIVDALSTKVLPNPEGQGTLVKVLSWYDNEWMYSCRCADIFHRLEKYL
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionGlyceraldehyde-3-phosphate dehydrogenase, enzyme
References for functionMarkoš, Anton, Anya Miretsky, and Miklós Müller. "A glyceraldehyde-3-phosphate dehydrogenase with eubacterial features in the amitochondriate eukaryote, Trichomonas vaginalis." Journal of molecular evolution 37.6 (1993): 631-643.
E.C. number1.2.1.12
Location of functional site(s)Active site:161 Binding site:243,191 Other functional site:188
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionbinds fibronectin fibronectin binding, and plasminogen and collagen
References for function Lama A, Kucknoor A, Mundodi V, Alderete JF. Glyceraldehyde-3-phosphate dehydrogenase is a surface-associated, fibronectin-binding protein of Trichomonas vaginalis. Infect Immun 2009, 77:2703-2711. PMID: 19380472
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments