Protein Information

General Information
MoonProt ID59
First appeared in release1.0
Name(s)GAPDH GapC Glyceraldehyde 3-phosphate dehydrogenase Gene Name: gap
UniProt IDQ9ALW2 (Q9ALW2_STRAG), Unreviewed
GO termsGO:0006006 glucose metabolic process GO:0055114 oxidation-reduction process GO:0016491 oxidoreductase activity GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0050661 NADP binding GO:0051287 NAD binding GO:0005515 protein binding
Organisms for which functions have been demonstratedStreptococcus agalactiae, Streptococcus - group B, serotype III/deltaepsilon, strain J48
Sequence length336
FASTA sequence>gi|21666599|gb|AAM73770.1|AF421899_1 glyceraldehyde-3-phosphate dehydrogenase [Streptococcus agalactiae] MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKDGGFEVNGSFVKVSAEREPANIDWATDGVDIVLEATGFFASKAAAEQHIHANGAKKVVITAPGGNDVKTVVYNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHGYTGDQMVLDGPHRGGDLRRARAAAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVAVLEKDTSVEEINAAMKAAANDSYGYTEDAIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTAQLVRTLEYFAKIAK
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionGlyceraldehyde 3-phosphate dehydrogenase, enzyme
References for functionSeifert KN, McArthur WP, Bleiweis AS, Brady LJ. Characterization of group B streptococcal glyceraldehyde-3-phosphate dehydrogenase: surface localization, enzymatic activity, and protein-protein interactions. Can J Microbiol. 2003 May;49(5):350-6. PMID: 12897829
E.C. number1.2.1.12
Location of functional site(s)Active site:152 Binding site:182,316,235,78,34,99,320,121 Metal binding site:24,27,21 Nucleotide binding site:12-13 Other functional site:179
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionplasminogen binding
References for functionSeifert KN, McArthur WP, Bleiweis AS, Brady LJ. Characterization of group B streptococcal glyceraldehyde-3-phosphate dehydrogenase: surface localization, enzymatic activity, and protein-protein interactions. Can J Microbiol. 2003 May;49(5):350-6. PMID: 12897829
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments