Protein Information

General Information
MoonProt ID60
First appeared in release1.0
Name(s)GAPDH GapA isoform Glyceraldehyde 3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase, type I Gene Name: gap2
UniProt IDQ81X74 (Q81X74_BACAN), Unreviewed
GO termsGO:0006006 glucose metabolic process GO:0055114 oxidation-reduction process GO:0016491 oxidoreductase activity GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0050661 NADP binding GO:0051287 NAD binding GO:0005515 protein binding
Organisms for which functions have been demonstratedBacillus anthracis
Sequence length334
FASTA sequence>gi|49181902|gb|AAT57278.1| glyceraldehyde 3-phosphate dehydrogenase [Bacillus anthracis str. Sterne] MTKIGINGFGRIGRNVFRAALNNSEVEVVAINDLTDAKTLAHLLKYDTVHGTLNAEVSANENSIVVNGKEIKVIAERDPAQLPWSDYGVEVVVESTGRFTKKSDAEKHLGGSVKKVIISAPASDEDITVVMGVNHEQYDAANHNVVSNASCTTNCLAPFAKVLNEKFGVKRGMMTTIHSYTNDQQILDLPHKDLRRARAAAENMIPTSTGAAKAVALVLPELKGKLNGGAVRVPTANVSLVDLVVELDKEVTVEEVNAAFKAAAEGELKGILGYSEEPLVSIDYNGCTASSTIDALSTMVMEGNMVKVLSWYDNETGYSNRVVDLAAYMTSKGL
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionglyceraldehyde 3-phosphate dehydrogenase, enzyme catalyzes the oxidative phosphorylation of D-glyceraldehyde- 3-phosphate (G-3-P) to 1,3-diphosphoglycerate in the presence of NAD+/NADP+ and inorganic phosphate (Pi)
References for functionMatta SK, Agarwal S, Bhatnagar R. Surface localized and extracellular Glyceraldehyde-3-phosphate dehydrogenase of Bacillus anthracis is a plasminogen binding protein. Biochim Biophys Acta. 2010 Nov;1804(11):2111-20. doi: 10.1016/j.bbapap.2010.08.004. Epub 2010 Aug 18. PMID: 20727989
E.C. number1.2.1.12
Location of functional site(s)Active site:151 Binding site:232,181 Other functional site:178
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionplasminogen binding
References for functionMatta SK, Agarwal S, Bhatnagar R. Surface localized and extracellular Glyceraldehyde-3-phosphate dehydrogenase of Bacillus anthracis is a plasminogen binding protein. Biochim Biophys Acta. 2010 Nov;1804(11):2111-20. doi: 10.1016/j.bbapap.2010.08.004. Epub 2010 Aug 18. PMID: 20727989
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments