Protein Information

General Information
MoonProt ID72
First appeared in release1.0
Name(s)Hsp60 chaperone 60 kDa chaperonin Cpn60 Gene Name: cpn60
UniProt IDQ8KP52 (Q8KP52_LISMN), Unreviewed
GO termsGO:0044267 cellular protein metabolic process GO:0000166 nucleotide binding GO:0005524 ATP binding GO:0005515 protein binding GO:0098631 cell adhesion mediator
Organisms for which functions have been demonstratedListeria
Sequence length549
FASTA sequence>gi|424714947|ref|YP_007015662.1| 60 kDa chaperonin [Listeria monocytogenes serotype 4b str. LL195] MIGGKYKMAKDIKFSEDARRAMLRGVDQLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDPFENMGAKLVSEVASKTNDVAGDGTTTATVLAQAMIQEGLKNVTAGANPVGVRRGIEKAVATAIEELKAISKPIESKESIAQVAAISSGDEEVGKLIAEAMERVGNDGVITIEESKGFATELDVVEGMQFDRGYTSPYMVTDSDKMEAVLEKPYILITDKKINNIQEILPVLEQVVQQGRPMLIIAEDVEGEAQATLVLNKLRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGQVITEDLGLELKTATVDQLGTANKVVVTKDDTTIVEGAGDSTQISARVNQIRAQMEETTSEFDREKLQERLAKLAGGVAVVKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVSIYNKVAALEAEGDVETGINIVLRSLEEPVRQIAHNAGLEGSVIVERLKHEAVGVGFNAANGEWVNMIDAGIVDPTKVTRSALQNASSVAALLLTTEAVVADKPDENGPAAVPDMGMGGMGGMM
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionHsp60 chaperone
References for functionBurkholder, Kristin M., and Arun K. Bhunia. "Listeria monocytogenes uses Listeria adhesion protein (LAP) to promote bacterial transepithelial translocation and induces expression of LAP receptor Hsp60." Infection and immunity 78.12 (2010): 5062-5073.
E.C. numberN/A
Location of functional site(s)
Cellular location of functionmitochondrial matrix
Comments
Function 2
Function descriptionadhesin
References for functionWampler JL, Kim KP, Jaradat Z, Bhunia AK. Heat shock protein 60 acts as a receptor for the Listeria adhesion protein in Caco-2 cells. Infect Immun. 2004 Feb;72(2):931-6. PMID: 14742538
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments