Protein Information

General Information
MoonProt ID73
First appeared in release1.0
Name(s)Hsp60 GroEL 60 kDa chaperonin Protein Cpn60 Gene Name: groL
UniProt IDP31294 (CH60_HAEDU), Reviewed
GO termsGO:0006457 protein folding GO:0042026 protein refolding GO:0044267 cellular protein metabolic process GO:0000166 nucleotide binding GO:0005524 ATP binding GO:0051082 unfolded protein binding GO:0005737 cytoplasm GO:0098631 cell adhesion mediator
Organisms for which functions have been demonstratedHaemophilus ducreyi
Sequence length547
FASTA sequence>gi|148892|gb|AAA24961.1| heat shock protein [Haemophilus ducreyi] MAIKDVKFGNDARVKMLKGVNILADAVKVTLGPKGRKVVLDKAYGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDVAGDGTTTATVLAQSIVSEGLRAVAAGMNPMDLKRGIDKAVAAVVEELKAISKPCETSKEIEQVGTISANSDETVGKLIAQAMEKVGKEGVITVEDGTGLDDALDVVEGMQFDRGYLSPYFINKPEAGTVELDNPYIILVDKKISNIREILPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIAILTAGTVISEEIGMELEKATLEELGQAKRVVITKDNTTIIDGIGDEAQIKARVVQIRQQIEDSTSDYDKEKLQERVAKLAGGVAVIKVGAATEVAMKEKKDRVDDALHATRAAVEEGIVPGGGVALVRAANKVSATLTGDNEEQNVGIKLALRAMEAPLRQIVENSGEDASVVARDVKDGSGNFGYNATTEEYGDMLEMGILDPTKVTRSALQFAASIAGLMITTECMITDLPKEDKLDAQAAMGGMGGMGGMM
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionHsp60, GroEL, Prevents misfolding and promotes the refolding and proper assembly of unfolded proteins
References for functionFrisk, A., C. A. Ison, and T. LagergÄrd. "GroEL heat shock protein of Haemophilus ducreyi: association with cell surface and capacity to bind to eukaryotic cells." Infection and immunity 66.3 (1998): 1252-1257.
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionadhesin - to glycosphinngolipids
References for functionPantzar M, Teneberg S, Lagerg?rd T. Binding of Haemophilus ducreyi to carbohydrate receptors is mediated by the 58.5-kDa GroEL heat shock protein. Microbes Infect. 2006 Aug;8(9-10):2452-8. PMID: 16880000
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments