Protein Information

General Information
MoonProt ID74
First appeared in release1.0
Name(s)Hsp60 GroEL 60 kDa chaperonin Protein Cpn60 Gene Name: groL
UniProt IDF7SCR2 (F7SCR2_LACJH)
GO termsGO:0006457 protein folding GO:0042026 protein refolding GO:0044267 cellular protein metabolic process GO:0000166 nucleotide binding GO:0005524 ATP binding GO:0051082 unfolded protein binding GO:0005737 cytoplasm GO:0005515 protein binding GO:0098631 cell adhesion mediator
Organisms for which functions have been demonstratedLactobacillus johnsonii La1 (NCC 533)
Sequence length543
FASTA sequence>gi|45645206|sp|Q9KJ23.2|CH60_LACJO RecName: Full=60 kDa chaperonin; AltName: Full=GroEL protein; AltName: Full=Protein Cpn60 MAKEIKFSENARHSLLKGVDKLADTVKTTLGPKGRNVVLEKSYGAPDITNDGVTIAKSIELENHFENMGAKLVSEAAQKTNDIAGDGTTTATVLTQAIVREGMKNVTAGANPVGIRRGIETATKAAVDELHKISHKVSTKDEIAQVASVSSASTEVGNLIADAMEKVGHDGVITIEESKGIDTELSVVEGMQFDRGYLSQYMVTDNDKMEADLDNPYILITDKKISNIQDILPLLQEIVQQGKSLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVISSDLGLELKDTKIDQLGKAGKVTVTKDSTTIVEGAGSKEAIAERVDQIKKQIADTTSDFDREKLQERLAKLAGGVAVIKVGAATETELKERKYRIEDALNATRAAVEEGYVAGGGTALVDVMKSIQGTVKGDSEDAETGVKIVMKALGAPVRQIAENAGKDGAVILDHLEHEDPEVGYNAATNKWENMVKAGIIDPTKVTRSALQNAASIAALLLTTEAVVADAPEDDKNQAPAAPNPGMGMGM
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionHsp60, GroEL, Prevents misfolding of proteins, promotes the refolding and correct assembly of unfolded proteins
References for functionWalker, D. Carey, Hany S. Girgis, and Todd R. Klaenhammer. "The groESL Chaperone Operon ofLactobacillus johnsonii." Applied and environmental microbiology 65.7 (1999): 3033-3041.
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionadhesin binds to mucins and epithelial cells
References for functionBergonzelli GE, Granato D, Pridmore RD, MarvinGuy LF, Donnicola D, Corth?syTheulaz IE. GroEL of Lactobacillus johnsonii La1 (NCC 533) is cell surface associated: potential role in interactions with the host and the gastric pathogen Helicobacter pylori. Infect Immun. 2006 Jan;74(1):425-34. PMID: 16368998
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments