Protein Information

General Information
MoonProt ID77
First appeared in release1.0
Name(s)Hsp60 GroEL 60 kDa chaperonin Protein Cpn60 Gene Name: groL
UniProt IDP0A1D3
GO termsGO:0006457 protein folding GO:0042026 protein refolding GO:0044267 cellular protein metabolic process GO:0000166 nucleotide binding GO:0005524 ATP binding GO:0051082 unfolded protein binding GO:0005737 cytoplasm GO:0005515 protein binding GO:0098631 cell adhesion mediator
Organisms for which functions have been demonstratedSalmonella typhimurium
Sequence length548 aa
FASTA sequence>sp|P0A1D3|CH60_SALTY 60 kDa chaperonin OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=groL PE=3 SV=2 MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVAAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKIADLKGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKSDAPDLGAAGGMGGMGGMGGMM
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionchaperonin, Prevents misfolding of proteins, promotes the refolding and proper assembly of unfolded proteins
References for functionRank, Roger G., et al. "Systemic immunization with Hsp60 alters the development of chlamydial ocular disease." Investigative ophthalmology & visual science 36.7 (1995): 1344-1351.
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionadhesin
References for functionEnsgraber M, Loos M. A 66-kilodalton heat shock protein of Salmonella typhimurium is responsible for binding of the bacterium to intestinal mucus. Infect Immun. 1992 Aug;60(8):3072-8. PMID: 1639475
E.C. numberN/A
Location of functional site(s)
Cellular location of functionsecreted
Comments