Protein Information

General Information
MoonProt ID84
First appeared in release1.0
Name(s)Peroxisomal catalase CTA1 Gene Name: CTA1
UniProt IDO13289 (CATA_CANAL), Reviewed
GO termsGO:0006979 response to oxidative stress GO:0009267 cellular response to starvation GO:0009405 pathogenesis GO:0030447 filamentous growth GO:0036170 filamentous growth of a population of unicellular organisms in response to starvation GO:0036171 filamentous growth of a population of unicellular organisms in response to chemical stimulus GO:0042542 response to hydrogen peroxide GO:0042743 hydrogen peroxide metabolic process GO:0042744 hydrogen peroxide catabolic process GO:0042744 hydrogen peroxide catabolic process GO:0051701 interaction with host GO:0055114 oxidation-reduction process GO:0070301 cellular response to hydrogen peroxide GO:0004096 catalase activity GO:0004601 peroxidase activity GO:0005515 protein binding GO:0016491 oxidoreductase activity GO:0020037 heme binding GO:0046872 metal ion binding GO:0005777 peroxisome GO:0009277 fungal-type cell wall GO:0005515 protein binding
Organisms for which functions have been demonstratedCandida albicans
Sequence length487
FASTA sequence>gi|21431745|sp|O13289.4|CATA_CANAL RecName: Full=Peroxisomal catalase MAPTFTNSNGQPIPEPFATQRVGQHGPLLLQDFNLIDSLAHFDRERIPERVVHAKGSGAYGVFEVTDDITDICAAKFLDTVGKKTRIFTRFSTVGGELGSADTARDPRGFATKIYTEEGNLDLVYNNTPVFFIRDPSKFPHFIHTQKRNPETHLKDANMFWDYLTSNEESIHQVMVLFSDRGTPASYREMNGYSGHTYKWSNKKGEWFYVQVHFISDQGIKTLNNEEAGALAGSNPDYAQEDLFKNIAAGNYPSWTAYIQTMTEAEAKEAEFSVFDLTKVWPHRKYPMRRFGKFTLNENPENYFAEVEQAAFSPAHTVPYMEPSADPVLQSRLFSYADTHRPHRLGTNYTQIPVNCPVTGAVFNPHSRDGAMTVNGNLGSHPNYLASDKPVEFKQFSSFQEDQEVWNGAATPFHWKATPADFKQAQELWKVLKRYPNQQEHLAHNIAVHAAGADAAIQDRVFAYFGKVSQDLADAIKKEVLELSPRK
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionPeroxisomal catalase (CTA1), protect cells from the toxic effects of hydrogen peroxide 2 H2O2 => O2 + 2 H2O
References for functionCuéllar-Cruz, Mayra, et al. "High resistance to oxidative stress in the fungal pathogen Candida glabrata is mediated by a single catalase, Cta1p, and is controlled by the transcription factors Yap1p, Skn7p, Msn2p, and Msn4p." Eukaryotic cell 7.5 (2008): 814-825.
E.C. number1.11.1.6
Location of functional site(s)Active site:53,126 Metal binding site:336
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionplasminogen binding
References for functionCrowe, J.D. et al. (2003) Candida albicans binds human plasminogen: identification of eight plasminogen-binding proteins. Mol Microbiol. 2003 Mar;47(6):1637-51. PMID: 12622818
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments