Protein Information

General Information
MoonProt ID88
First appeared in release1.0
Name(s)Phosphoglycerate kinase PGK1 Gene Name: pgk
UniProt IDA0A0G7HBY7
GO termsGO:0006096 glycolysis GO:0016310 phosphorylation GO:0000166 nucleotide binding GO:0004618 phosphoglycerate kinase activity GO:0005524 ATP binding GO:0016301 kinase activity GO:0016740 transferase activity GO:0005737 cytoplasm GO:0005515 protein binding
Organisms for which functions have been demonstratedStreptococcus - oral streptococci (S. anginosus and S. oralis)
Sequence length396 aa
FASTA sequence>tr|A0A0G7HBY7|A0A0G7HBY7_9STRE Phosphoglycerate kinase OS=Streptococcus equi subsp. equi GN=pgk_1 PE=3 SV=1 MAKKIVTDLELKGKTVLVRADFNVPMKDGEITDDNRIVQAIPTIKYIIEQGGKVVLFSHLGKVKEESDKAALTLKPVANALTEKLGEEVTFVPETRGETLEQSVKDLNEGDVLLVENTRFEDVDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGIASNLETVAGFLMEKEIKYIGGVVENPDKPVVAILGGAKVSDKIGVITNLLKIADKVLIGGGMSYTFFKAQGKEIGLSLLEKDKVDFAKELLDRAGDQIVLPVDCKVAKEFSNDAEITEVSVDDIPADQEAMDIGPKSVELFKEQLQGAHTVVWNGPMGVFELSNFAKGTIGVCEAIAELKDANTIIGGGDSAAAAISLGYGDDFSHISTGGGASLEYLEGKELPGVVAIANK
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionPhosphoglycerate kinase, enzyme ADP + 1,3-bisphosphoglycerate => ATP + 3-phospho-D-glycerate Carbohydrate degradation, glycolysis
References for functionAbbe, Kazuhiko, Shoko Takahashi, and Tadashi Yamada. "Purification and properties of pyruvate kinase from Streptococcus sanguis and activator specificity of pyruvate kinase from oral streptococci." Infection and immunity 39.3 (1983): 1007-1014.
E.C. number2.7.2.3
Location of functional site(s)Binding site:206,119,156,36,325 Nucleotide binding site:352-355
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionplasminogen binding
References for functionKinnby B, Booth NA, Svensater G. Plasminogen binding by oral streptococci from dental plaque and inflammatory lesions.Microbiology. 2008 Mar;154(Pt 3):924-31. doi: 10.1099/mic.0.2007/013235-0. PMID: 18310038
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments