Protein Information

General Information
MoonProt ID92
First appeared in release1.0
Name(s)Pyruvate dehydrogenase (E1 beta subunit, PDH-B) Pyruvate dehydrogenase E1 component subunit beta Gene Name: pdhB
UniProt IDP75391 (ODPB_MYCPN), Reviewed
GO termsGO:0006096 glycolysis GO:0008152 metabolic process GO:0055114 oxidation-reduction process GO:0003824 catalytic activity GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity GO:0016491 oxidoreductase activity GO:0005515 protein binding GO:0098631 cell adhesion mediator
Organisms for which functions have been demonstratedMycoplasma pneumoniae
Sequence length327
FASTA sequence>sp|P75391|ODPB_MYCPN Pyruvate dehydrogenase E1 component subunit beta OS=Mycoplasma pneumoniae (strain ATCC 29342 / M129) GN=pdhB PE=3 SV=1 MSKTIQANNIEALGNAMDLALERDPNVVLYGQDAGFEGGVFRATKGLQKKYGEERVWDCPIAEAAMAGIGVGAAIGGLKPIVEIQFSGFSFPAMFQIFTHAARIRNRSRGVYTCPIIVRMPMGGGIKALEHHSETLEAIYGQIAGLKTVMPSNPYDTKGLFLAAVESPDPVVFFEPKKLYRAFRQEIPADYYTVPIGQANLISQGNNLTIVSYGPTMFDLINMVYGGELKDKGIELIDLRTISPWDKETVFNSVKKTGRLLVVTEAAKTFTTSGEIIASVTEELFSYLKAAPQRVTGWDIVVPLARGEHYQFNLNARILEAVNQLLK
Structure Information
PDB ID
Quaternary structure
Function 1
Function descriptionPyruvate dehydrogenase, enzyme The pyruvate dehydrogenase complex catalyzes the overall conversion pyruvate => acetyl-CoA and CO2. Pyruvate dehydrogenase (E1) is one of the enzyme components of the complex
References for function
E.C. number1.2.4.1
Location of functional site(s)Binding site:63
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionfibrinogen binding
References for functionDallo SF, Kannan TR, Blaylock MW, Baseman JB. Elongation factor Tu and E1 beta subunit of pyruvate dehydrogenase complex act as fibronectin binding proteins in Mycoplasma pneumoniae. Mol Microbiol. 2002 Nov. PMID: 12421310
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments